ea0034p364 | Steroids | SFEBES2014
Razak Nur Izah Ab
, Diver Louise
, Alvarez-Madrazo Samantha
, Robertson Stacy
, McBride Martin
, Stewart Paul
, Connell John
, MacKenzie Scott
, Davies Eleanor
Hypertension is a common risk factor for cardiovascular disease and up to 15% of hypertensive patients are now known to have primary aldosteronism (PA), where the adrenal glands secrete inappropriately high levels of the steroid hormone aldosterone. Of these cases, almost half are due to the presence of unilateral aldosterone-producing adenoma (APA). Aldosterone is synthesised in the zona glomerulosa of the adrenal cortex, with the final stages of production catalysed by aldos...